S74R (p.Ser74Arg) variant of TAS2R5 (Taste receptor type 2 member 5)
S74R (p.Ser74Arg) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
S74R (p.Ser74Arg) variant details
- p.Ser74Arg
- gnomAD 7-141790583-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.29
- MetaLR 0.07
- MetaSVM -1.02
- CADD 6.92
- Most common in the Ashkenazi Jewish population (allele frequency 0.00058)
- Structural context available
- Literature evidence available