R76S (p.Arg76Ser) variant of TAS2R5 (Taste receptor type 2 member 5)
R76S (p.Arg76Ser) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R76S (p.Arg76Ser) variant details
- p.Arg76Ser
- 1000Genomes rs201786698
- ExAC rs201786698
- TOPMed rs201786698
- gnomAD rs201786698
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.0996
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.00
- MetaSVM -0.94
- CADD 0.23
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the 1KG:YRI population (allele frequency 0.13)
- Structural context available