R76H (p.Arg76His) variant of TAS2R5 (Taste receptor type 2 member 5)
R76H (p.Arg76His) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
R76H (p.Arg76His) variant details
- p.Arg76His
- rs200318022
- NCI-TCGA Cosmic COSV5609
- 1000Genomes rs200318022
- ExAC rs200318022
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.085
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.00
- MetaSVM -0.92
- CADD 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:YRI population (allele frequency 0.13)
- Structural context available