R37T (p.Arg37Thr) variant of TAS2R5 (Taste receptor type 2 member 5)
R37T (p.Arg37Thr) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R37T (p.Arg37Thr) variant details
- p.Arg37Thr
- rs1482588189
- TOPMed rs1482588189
- gnomAD rs1482588189
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.21
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.19
- MetaSVM -0.96
- CADD 15.70
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available