P70S (p.Pro70Ser) variant of TAS2R5 (Taste receptor type 2 member 5)
P70S (p.Pro70Ser) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P70S (p.Pro70Ser) variant details
- p.Pro70Ser
- NCI-TCGA Cosmic COSV5609
- gnomAD rs1800431397
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.01
- ESM-1b 0.00
- AlphaMissense 0.24
- MetaLR 0.00
- MetaSVM -0.93
- CADD 2.81
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available