L81H (p.Leu81His) variant of TAS2R5 (Taste receptor type 2 member 5)
L81H (p.Leu81His) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L81H (p.Leu81His) variant details
- p.Leu81His
- gnomAD 7-141790603-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.12
- ESM-1b 1.00
- AlphaMissense 0.38
- MetaLR 0.01
- MetaSVM -0.93
- CADD 17.20
- Most common in the 1KG:FIN population (allele frequency 0.0051)
- Structural context available
- Literature evidence available