L66S (p.Leu66Ser) variant of TAS2R5 (Taste receptor type 2 member 5)
L66S (p.Leu66Ser) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L66S (p.Leu66Ser) variant details
- p.Leu66Ser
- ExAC rs753562198
- TOPMed rs753562198
- gnomAD rs753562198
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.60
- MetaLR 0.10
- MetaSVM -0.97
- CADD 11.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available