L57I (p.Leu57Ile) variant of TAS2R5 (Taste receptor type 2 member 5)
L57I (p.Leu57Ile) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L57I (p.Leu57Ile) variant details
- p.Leu57Ile
- TOPMed rs1224044365
- gnomAD rs1224044365
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.12
- ESM-1b 0.00
- AlphaMissense 0.12
- MetaLR 0.09
- MetaSVM -1.05
- CADD 8.93
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available