L21F (p.Leu21Phe) variant of TAS2R5 (Taste receptor type 2 member 5)
L21F (p.Leu21Phe) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- TOPMed rs1800429151
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.24
- MetaLR 0.00
- MetaSVM -0.92
- CADD 8.36
- Most common in the HGDP:DRUZE population (allele frequency 0.1)
- Structural context available