L18F (p.Leu18Phe) variant of TAS2R5 (Taste receptor type 2 member 5)
L18F (p.Leu18Phe) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L18F (p.Leu18Phe) variant details
- p.Leu18Phe
- ExAC rs760959195
- gnomAD rs760959195
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.15
- MetaSVM -1.00
- CADD 12.40
- Most common in the Ashkenazi Jewish population (allele frequency 0.00058)
- Structural context available