I22T (p.Ile22Thr) variant of TAS2R5 (Taste receptor type 2 member 5)
I22T (p.Ile22Thr) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I22T (p.Ile22Thr) variant details
- p.Ile22Thr
- ExAC rs750558319
- TOPMed rs750558319
- gnomAD rs750558319
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.00
- MetaSVM -0.92
- CADD 6.78
- Most common in the HGDP:ADYGEI population (allele frequency 0.088)
- Structural context available