I22L (p.Ile22Leu) variant of TAS2R5 (Taste receptor type 2 member 5)
I22L (p.Ile22Leu) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
I22L (p.Ile22Leu) variant details
- p.Ile22Leu
- gnomAD 7-141790425-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0751
- REVEL 0.02
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.00
- MetaSVM -0.95
- CADD 0.18
- Most common in the HGDP:DRUZE population (allele frequency 0.1)
- Structural context available
- Literature evidence available