I22K (p.Ile22Lys) variant of TAS2R5 (Taste receptor type 2 member 5)
I22K (p.Ile22Lys) in TAS2R5 (Taste receptor type 2 member 5) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
I22K (p.Ile22Lys) variant details
- p.Ile22Lys
- gnomAD 7-141790423-T-TGA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.548
- CADD 21.70
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.15)
- Structural context available
- Literature evidence available