I22F (p.Ile22Phe) variant of TAS2R5 (Taste receptor type 2 member 5)
I22F (p.Ile22Phe) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
I22F (p.Ile22Phe) variant details
- p.Ile22Phe
- gnomAD 7-141790425-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.00
- MetaSVM -0.94
- CADD 11.00
- Most common in the HGDP:PIMA population (allele frequency 0.091)
- Structural context available
- Literature evidence available