I19L (p.Ile19Leu) variant of TAS2R5 (Taste receptor type 2 member 5)
I19L (p.Ile19Leu) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
I19L (p.Ile19Leu) variant details
- p.Ile19Leu
- gnomAD 7-141790416-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.05
- MetaSVM -1.03
- CADD 6.94
- Most common in the HGDP:DRUZE population (allele frequency 0.1)
- Structural context available
- Literature evidence available