G23R (p.Gly23Arg) variant of TAS2R5 (Taste receptor type 2 member 5)
G23R (p.Gly23Arg) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G23R (p.Gly23Arg) variant details
- p.Gly23Arg
- NCI-TCGA Cosmic COSV5609
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.26
- ESM-1b 1.00
- AlphaMissense 0.70
- MetaLR 0.28
- MetaSVM -0.59
- CADD 19.40
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the HGDP:PATHAN population (allele frequency 0.083)
- Structural context available