E16A (p.Glu16Ala) variant of TAS2R5 (Taste receptor type 2 member 5)
E16A (p.Glu16Ala) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E16A (p.Glu16Ala) variant details
- p.Glu16Ala
- gnomAD rs1186012404
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.18
- ESM-1b 0.14
- AlphaMissense 0.40
- MetaLR 0.20
- MetaSVM -0.94
- CADD 22.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available