A52T (p.Ala52Thr) variant of TAS2R5 (Taste receptor type 2 member 5)
A52T (p.Ala52Thr) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A52T (p.Ala52Thr) variant details
- p.Ala52Thr
- TOPMed rs1408887785
- gnomAD rs1408887785
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.16
- ESM-1b 0.00
- AlphaMissense 0.34
- MetaLR 0.23
- MetaSVM -0.84
- CADD 20.70
- Most common in the HGDP:PIMA population (allele frequency 0.091)
- Structural context available