A52S (p.Ala52Ser) variant of TAS2R5 (Taste receptor type 2 member 5)
A52S (p.Ala52Ser) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A52S (p.Ala52Ser) variant details
- p.Ala52Ser
- TOPMed rs1408887785
- gnomAD rs1408887785
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.18
- MetaLR 0.10
- MetaSVM -0.93
- CADD 9.67
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available