Y79C (p.Tyr79Cys) variant of STAT3 (P40763)
Y79C (p.Tyr79Cys) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y79C (p.Tyr79Cys) variant details
- p.Tyr79Cys
- gnomAD rs1281834571
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.25
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available