Y68H (p.Tyr68His) variant of STAT3 (P40763)
Y68H (p.Tyr68His) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y68H (p.Tyr68His) variant details
- p.Tyr68His
- TOPMed rs1187104418
- gnomAD rs1187104418
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.26
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available