W110L (p.Trp110Leu) variant of STAT3 (P40763)
W110L (p.Trp110Leu) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
W110L (p.Trp110Leu) variant details
- p.Trp110Leu
- Ensembl rs2144978637
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.33
- CADD 24.30
- PolyPhen-2 0.98
- SIFT 0.42
- Population evidence available
- Structural context available