T138M (p.Thr138Met) variant of STAT3 (P40763)
T138M (p.Thr138Met) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T138M (p.Thr138Met) variant details
- p.Thr138Met
- cosmic curated COSV52892
- Ensembl rs2144895871
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.22
- CADD 24.10
- PolyPhen-2 0.47
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available