T133P (p.Thr133Pro) variant of STAT3 (P40763)
T133P (p.Thr133Pro) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
T133P (p.Thr133Pro) variant details
- p.Thr133Pro
- TOPMed rs1442943787
- gnomAD rs1442943787
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.45
- CADD 22.50
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available