T118I (p.Thr118Ile) variant of STAT3 (P40763)
T118I (p.Thr118Ile) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T118I (p.Thr118Ile) variant details
- p.Thr118Ile
- TOPMed rs1234764558
- gnomAD rs1234764558
- Missense
- Variant Prioritization Score for Impact Estimate 0.523
- REVEL 0.33
- CADD 25.70
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available