Q66E (p.Gln66Glu) variant of STAT3 (P40763)
Q66E (p.Gln66Glu) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
Q66E (p.Gln66Glu) variant details
- p.Gln66Glu
- ESP rs375760579
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.21
- CADD 22.40
- PolyPhen-2 0.89
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available