P98T (p.Pro98Thr) variant of STAT3 (P40763)
P98T (p.Pro98Thr) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
P98T (p.Pro98Thr) variant details
- p.Pro98Thr
- cosmic curated COSV10959
- Missense
- Variant Prioritization Score for Impact Estimate 0.851
- REVEL 0.89
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available