N130S (p.Asn130Ser) variant of STAT3 (P40763)
N130S (p.Asn130Ser) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
N130S (p.Asn130Ser) variant details
- p.Asn130Ser
- gnomAD rs1195908534
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.16
- CADD 16.80
- PolyPhen-2 0.00
- SIFT 0.68
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available