K153N (p.Lys153Asn) variant of STAT3 (P40763)
K153N (p.Lys153Asn) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
K153N (p.Lys153Asn) variant details
- p.Lys153Asn
- cosmic curated COSV52895
- Ensembl rs2144895357
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.08
- CADD 19.60
- PolyPhen-2 0.32
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available