H58Y (p.His58Tyr) variant of STAT3 (P40763)

H58Y (p.His58Tyr) in STAT3 (P40763) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of Hyper-IgE recurrent infection syndrome 1, autosomal dominant; STAT3 gain of func. The record also includes structural context.

H58Y (p.His58Tyr) variant details