F33V (p.Phe33Val) variant of STAT3 (P40763)
F33V (p.Phe33Val) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
F33V (p.Phe33Val) variant details
- p.Phe33Val
- gnomAD rs1340218209
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.28
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available