A120V (p.Ala120Val) variant of STAT3 (P40763)
A120V (p.Ala120Val) in STAT3 (P40763) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A120V (p.Ala120Val) variant details
- p.Ala120Val
- Ensembl rs2144978133
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.13
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available