T45S (p.Thr45Ser) variant of SRD5A2 (P31213)
T45S (p.Thr45Ser) in SRD5A2 (P31213) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T45S (p.Thr45Ser) variant details
- p.Thr45Ser
- ExAC rs776884291
- TOPMed rs776884291
- gnomAD rs776884291
- Missense
- Variant Prioritization Score for Impact Estimate 0.0791
- CADD 1.24
- PolyPhen-2 0.01
- SIFT 0.71
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available