T45I (p.Thr45Ile) variant of SRD5A2 (P31213)
T45I (p.Thr45Ile) in SRD5A2 (P31213) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T45I (p.Thr45Ile) variant details
- p.Thr45Ile
- ExAC rs776884291
- TOPMed rs776884291
- gnomAD rs776884291
- Missense
- Variant Prioritization Score for Impact Estimate 0.0835
- CADD 2.58
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available