P106A (p.Pro106Ala) variant of SRD5A2 (P31213)
P106A (p.Pro106Ala) in SRD5A2 (P31213) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
P106A (p.Pro106Ala) variant details
- p.Pro106Ala
- ExAC rs769436494
- TOPMed rs769436494
- gnomAD rs769436494
- Missense
- Variant Prioritization Score for Impact Estimate 0.533
- CADD 17.20
- PolyPhen-2 0.21
- SIFT 0.46
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available