L68I (p.Leu68Ile) variant of SRD5A2 (P31213)
L68I (p.Leu68Ile) in SRD5A2 (P31213) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L68I (p.Leu68Ile) variant details
- p.Leu68Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- CADD 20.80
- PolyPhen-2 0.40
- SIFT 0.09
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available