F92L (p.Phe92Leu) variant of SRD5A2 (P31213)
F92L (p.Phe92Leu) in SRD5A2 (P31213) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
F92L (p.Phe92Leu) variant details
- p.Phe92Leu
- TOPMed rs895624262
- gnomAD rs895624262
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- CADD 22.50
- PolyPhen-2 0.47
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available