P22P (p.Pro22Pro) variant of SPAST (Spastin)
P22P (p.Pro22Pro) in SPAST (Spastin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P22P (p.Pro22Pro) variant details
- p.Pro22Pro
- rs1262209200
- gnomAD 2-32063897-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.364
- CADD 14.90
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- Literature evidence available