P21T (p.Pro21Thr) variant of SPAST (Spastin)
P21T (p.Pro21Thr) in SPAST (Spastin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P21T (p.Pro21Thr) variant details
- p.Pro21Thr
- Ensembl rs865867577
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.29
- CADD 21.90
- PolyPhen-2 0.06
- SIFT 0.11
- Population evidence available
- Structural context available