P21P (p.Pro21Pro) variant of SPAST (Spastin)
P21P (p.Pro21Pro) in SPAST (Spastin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
P21P (p.Pro21Pro) variant details
- p.Pro21Pro
- rs1676388360
- gnomAD 2-32063894-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.686
- CADD 15.10
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available