G15G (p.Gly15Gly) variant of SPAST (Spastin)
G15G (p.Gly15Gly) in SPAST (Spastin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
G15G (p.Gly15Gly) variant details
- p.Gly15Gly
- rs1221944437
- gnomAD 2-32063876-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.546
- CADD 14.40
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available