V24D (p.Val24Asp) variant of SOS2 (Son of sevenless homolog 2)
V24D (p.Val24Asp) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
V24D (p.Val24Asp) variant details
- p.Val24Asp
- ExAC rs764249804
- gnomAD rs764249804
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.62
- MetaLR 0.52
- MetaSVM -0.01
- CADD 25.10
- PolyPhen-2 0.06
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available