T77I (p.Thr77Ile) variant of SOS2 (Son of sevenless homolog 2)
T77I (p.Thr77Ile) in SOS2 (Son of sevenless homolog 2) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The record also includes variant effect predictions, population frequency data, and structural context.
T77I (p.Thr77Ile) variant details
- p.Thr77Ile
- 1000Genomes rs565261873
- ExAC rs565261873
- TOPMed rs565261873
- gnomAD rs565261873
- Likely benign
- Missense
- MetaLR 0.64
- MetaSVM 0.35
- SIFT 0.04
- EBI: Likely benign
- UniProt: Likely benign
- Population evidence available
- Structural context available