S92Y (p.Ser92Tyr) variant of SOS2 (Son of sevenless homolog 2)
S92Y (p.Ser92Tyr) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
S92Y (p.Ser92Tyr) variant details
- p.Ser92Tyr
- TOPMed rs1886468962
- gnomAD rs1886468962
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- REVEL 0.53
- MetaLR 0.69
- MetaSVM 0.41
- CADD 27.50
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available