R153W (p.Arg153Trp) variant of SOS2 (Son of sevenless homolog 2)
R153W (p.Arg153Trp) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
R153W (p.Arg153Trp) variant details
- p.Arg153Trp
- Ensembl rs778339464
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.74
- MetaLR 0.48
- MetaSVM 0.05
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available