Q91L (p.Gln91Leu) variant of SOS2 (Son of sevenless homolog 2)
Q91L (p.Gln91Leu) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
Q91L (p.Gln91Leu) variant details
- p.Gln91Leu
- Ensembl rs1566477467
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.57
- MetaLR 0.58
- MetaSVM 0.19
- CADD 24.10
- PolyPhen-2 0.12
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available