Q31R (p.Gln31Arg) variant of SOS2 (Son of sevenless homolog 2)
Q31R (p.Gln31Arg) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
Q31R (p.Gln31Arg) variant details
- p.Gln31Arg
- Ensembl rs2139796369
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.49
- MetaLR 0.69
- MetaSVM 0.41
- CADD 23.90
- PolyPhen-2 0.89
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available