F11L (p.Phe11Leu) variant of SOS2 (Son of sevenless homolog 2)
F11L (p.Phe11Leu) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
F11L (p.Phe11Leu) variant details
- p.Phe11Leu
- gnomAD rs1221101657
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.30
- MetaLR 0.41
- MetaSVM -0.44
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available