D89G (p.Asp89Gly) variant of SOS2 (Son of sevenless homolog 2)
D89G (p.Asp89Gly) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
D89G (p.Asp89Gly) variant details
- p.Asp89Gly
- ExAC rs780385201
- gnomAD rs780385201
- Missense
- Variant Prioritization Score for Impact Estimate 0.76
- REVEL 0.84
- MetaLR 0.71
- MetaSVM 0.56
- CADD 28.40
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available