A26T (p.Ala26Thr) variant of SOS2 (Son of sevenless homolog 2)
A26T (p.Ala26Thr) in SOS2 (Son of sevenless homolog 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
A26T (p.Ala26Thr) variant details
- p.Ala26Thr
- gnomAD rs1453155265
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.56
- MetaLR 0.57
- MetaSVM 0.26
- CADD 24.00
- PolyPhen-2 0.21
- SIFT 0.08
- Population evidence available
- Structural context available